Can IgG test go negative without treatment?
Posted: Tue Sep 25, 2018 12:13 pm
Hello,
I am new here so I'll just start off and give some of my background. I am 36 years old, male, caucasian and developed a small duodenal ulcer 3 years ago. I was tested negative for h pylori with biopsy twice. However, I had been taking PPIs, bismuth, and antacids days prior to these tests so I am worried the result is a false negative.
Strangely in 2013, 2 years before the ulcer I started having gastritis and was tested positive for h pylori IgG on the serum test:
H pylori IgG Antibody: 3.2 where >2.3 or greater is positive.
The IgM was 0.4 and IgA was 0.9, both negative.
Also I have not been treated with antibiotics.
So my question is is there a chance I could still have h pylori infection, maybe low level?
If I have the igG h pylori antibody, can a previous infection spontaneously go away even if I have never taken triple therapy antibiotics?
I have had a negative breath test (took bismuth about 2 1/2 weeks prior and h2 blockers 48-72 hours prior).
My gastroenterologist doesn't think it is h pylori. I still have pains under the ribcage --- after 3 years of taking ppis and h2 blockers.
I am new here so I'll just start off and give some of my background. I am 36 years old, male, caucasian and developed a small duodenal ulcer 3 years ago. I was tested negative for h pylori with biopsy twice. However, I had been taking PPIs, bismuth, and antacids days prior to these tests so I am worried the result is a false negative.
Strangely in 2013, 2 years before the ulcer I started having gastritis and was tested positive for h pylori IgG on the serum test:
H pylori IgG Antibody: 3.2 where >2.3 or greater is positive.
The IgM was 0.4 and IgA was 0.9, both negative.
Also I have not been treated with antibiotics.
So my question is is there a chance I could still have h pylori infection, maybe low level?
If I have the igG h pylori antibody, can a previous infection spontaneously go away even if I have never taken triple therapy antibiotics?
I have had a negative breath test (took bismuth about 2 1/2 weeks prior and h2 blockers 48-72 hours prior).
My gastroenterologist doesn't think it is h pylori. I still have pains under the ribcage --- after 3 years of taking ppis and h2 blockers.