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Diagnosing from a biopsy

There are several types of tests for H.pylori. The major ones have a their own forum.

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JustAsking55
Posts: 1
Joined: Fri Jul 15, 2016 2:26 am

Diagnosing from a biopsy

Post by JustAsking55 » Fri Jul 15, 2016 2:43 am

Hi,

I had a stool test in 2014 which was negative. A year later I had an endoscopy. It only took biopsies from the body of the stomach, not antrum, and the results say that small numbers of surface h pylori were seen. The gastroenterologist said that nothing showed up in the endoscopy which explained my symptoms (I didn't have the report when I was discussing the endoscopy with him).

I'd like to know are small number of surface bacteria in the body of the stomach enough for a diagnosis of an active infection? Does anyone have a link to a web page which states something like this which I can show to my GP?

Does anyone know of any research showing that the stool sample test is not reliable in people with anti parietal cell antibodies?

Thanks.

Helico_expert
Site Admin
Posts: 2432
Joined: Wed Mar 02, 2011 7:20 am

Re: Diagnosing from a biopsy

Post by Helico_expert » Tue Jul 19, 2016 9:36 am

if you can see one, there are many more. Your doctor who perform endoscopy should have done a CLOtest on spot to determine presence of H. pylori.

Histology that shows surface HP like organism could mean other bacteria from saliva. In the histology report, it should at least state if you have active or chronic gastritis. That may give us a hint if you are still carrying H. pylori.

Lenochka
Posts: 7
Joined: Sun Aug 14, 2016 12:51 am

Re: Diagnosing from a biopsy

Post by Lenochka » Fri Aug 26, 2016 12:12 am

[quote="Helico_expert"]
Dear hp expert can you tell how taking ppi effect on result of biopsy and culture test. I am waiting result of biopsy. I am seek from September 2015. Please answer my question. Thanks.

Helico_expert
Site Admin
Posts: 2432
Joined: Wed Mar 02, 2011 7:20 am

Re: Diagnosing from a biopsy

Post by Helico_expert » Fri Aug 26, 2016 4:03 pm

PPI reduce the acid in the stomach. So,
1. H. pylori was tricked to make too much ammonia and killed itself (but some smart one will survive).
2. Other bacteria start growing and suppress the growth of H. pylori.

So patient who take PPI will have less chance in culturing. Either the bacterial load is too low or there is too many contamination and H. pylori cannot be seen.

Lenochka
Posts: 7
Joined: Sun Aug 14, 2016 12:51 am

Re: Diagnosing from a biopsy

Post by Lenochka » Sat Aug 27, 2016 12:00 am

Thanks for the answer. My doctor told it's ok to take PPI before endoscopy, and I asked him to do culture test for my cost.
I wish gastrologiests knew more about h pylory !!!!

Helico_expert
Site Admin
Posts: 2432
Joined: Wed Mar 02, 2011 7:20 am

Re: Diagnosing from a biopsy

Post by Helico_expert » Mon Aug 29, 2016 9:26 am

yea, the biology of H. pylori was not easy. Took Prof. Marshall's team a year to figure out how to culture H. pylori. Now that there is a cure, doctors pay less attention to it. But the good one would know what's best to kill it.

mariasherapowa
Posts: 1
Joined: Mon Aug 29, 2016 5:14 pm

selenium can be toxic and even reduce

Post by mariasherapowa » Mon Aug 29, 2016 5:16 pm

selenium can be toxic and even reduce androgenic hormonal or androgenic Blackcore Edge
hormonal or testosterone levels.

Lenochka
Posts: 7
Joined: Sun Aug 14, 2016 12:51 am

Re: Diagnosing from a biopsy

Post by Lenochka » Mon Aug 29, 2016 11:39 pm

Helico_expert wrote:yea, the biology of H. pylori was not easy. Took Prof. Marshall's team a year to figure out how to culture H. pylori. Now that there is a cure, doctors pay less attention to it. But the good one would know what's best to kill it.
Dear helico expert can you recommend me good hp Doctor in USA?
If my GI does not help me this time I am absolutely lost. On the top of all I have hepatitis B. All my life is going to pieces.
Thanks to prof. Marshall and all his team for their work!!!!

Helico_expert
Site Admin
Posts: 2432
Joined: Wed Mar 02, 2011 7:20 am

Re: Diagnosing from a biopsy

Post by Helico_expert » Tue Aug 30, 2016 9:13 am

Prof. David Graham is a guru in this field. You can try contact him

https://www.bcm.edu/people/view/david-g ... 0027880ca6

jonur
Posts: 2
Joined: Sat May 26, 2018 11:20 pm

Re: Diagnosing from a biopsy

Post by jonur » Sat May 26, 2018 11:58 pm

I know this is an older thread, but in case it gets read again, I just wanted to ask-I know PPI use can effect test results for H. Pylori, but is this if you are on them long-term or it does not matter? I took a Nexium (one pill 40mg) 3 days before my test and was wondering if this is why I was tested negative via biopsy-was also on probiotics, I had just started about 10 days before the endoscopy, but I couldn't find too much research on the effects of probiotics + h.pylori testing.

My GI doctor didn't tell me they would be looking for that-if she had, I would have done everything in my power to have a clearer scope.

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