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C13 / C14 what is the difference !

Breath tests are the most accurate way of detecting H.pylori without actually having an endoscopy (stomach examination). Breath tests are especially useful after treatment to make sure H.pylori is cured. Urea breath tests are known to be completely harmless. Either C14-urea or C13-urea tests are used. Read about them at the diagnosis section at where a diagram can be found. C14-urea breath tests use a radioactive tracer but such a tiny amount that it can be used safely at any age. It is a 15 minute test, convenient and inexpensive. The C13-urea test uses a stable isotope of carbon which is also harmless but requires two breath samples and takes about 30 minutes. Both tests have accuracy greater than 90%.

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C13 / C14 what is the difference !

Post by kelthuzad » Fri Jan 01, 2016 8:02 am

i want to equip my clinical laboratory with the HP urea breath test then i got to think : C13/C14 !!!
i don't seem to find the point behind making c13 or c14 since they seem to have same performance .
i thought at first it was a safety matter (radioactivity of C14 even if it seems negligible)
then after hours of digging i found that C14 is cheaper and easier to handle then C13

anyone have a clue please ????

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Re: C13 / C14 what is the difference !

Post by Helico_expert » Tue Jan 12, 2016 10:16 pm

C13 can be found naturally in your body. That's why you need to measure your baseline before taking the C13 pill. Yes, you are right it is harder to process and without experience, result can easily be messed up. Because C13 is simply everywhere.

C14 on the other hand, it's radioactive, and which in my opinion, less likely to mess up and more accurate. The radiation is very low and it is even approved to be used by pregnant women and children. Nevertheless, it is still a radioactive element and many people is afraid of it.

Let me know if i have not answered your question.

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Re: C13 / C14 what is the difference !

Post by michaeljonson » Wed May 25, 2016 7:56 pm

Helico_expert, thank you for explaining the difference.
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