I was under the impression that H Pylori can never become resistant to Amoxicillin. But I recently came across an article that claimed nearly 8% resistance among the test subjects. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513510/)
Is the study accurate? What is the reason for H Pylori to be unable to be resistant to Amoxicillin?
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Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
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欧洲幽门螺杆菌治疗共识 5
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Should you have any problem in posting, registering, or login, please do not hesitate to contact the admin at Marshall.centre(at)gmail(dot)com. In the subject, please use "Help needed for www.helico.com"
Advertisement is not allowed. While we encourage discussion, please try not to promote your website, goods, or unproven treatment here.
This is a non-profit website. We will try our best to help anyone that has question about H. pylori and their treatment. We shall provide the most accurate answer about H. pylori. You can help us by clicking here to keep this forum alive.
Some useful guides
How to post in the forum?
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
The 5th Chinese Helicobacter treatment consensus
How long should I wait before doing follow up breath/stool test?
If you are confirmed with H. pylori, in your convenient time, please help us with the symptoms survey that you are experiencing.
Symptoms survey
(contributed by frostyfeet)
此网站免费然您阅读。若想分享心得或提问,请先注册。
若有困难注册,请联络站长 Marshall.centre(at)gmail(dot)com。标题请用 "Help needed for www.helico.com"
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此网站是非盈利网站。我们会尽最大能力提供任何有关幽门螺杆菌的讯息。您的捐款可以让我们继续帮助更多的病人。
指南
如何贴文?
欧洲幽门螺杆菌治疗共识 5
第五次全国幽门螺杆菌感染处理共识报告
用药后,多久以后可以再做吹气测试?
RESISTANCE TO AMOXICILLIN IN H PYLORI?
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Re: RESISTANCE TO AMOXICILLIN IN H PYLORI?
It's a bit awkward. because it is our group that publish this paper. It's a collaboration between our group and the Indian group. We helped them with the genome sequencing while they provide the antibiotic resistant profile. It is almost unbelievable to see such high number of Amoxicillin resistant H. pylori. Usually these resistance results are not reproducible.
We also have another collaborator in Guiyang, China, that claim to have 13% Amoxicillin resistant strains. We requested a repeat of the experiment, and they very kindly did it, and no longer able to see those resistant cases again.
We also have another collaborator in Guiyang, China, that claim to have 13% Amoxicillin resistant strains. We requested a repeat of the experiment, and they very kindly did it, and no longer able to see those resistant cases again.
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Re: RESISTANCE TO AMOXICILLIN IN H PYLORI?
So what you're saying is the numbers are not accurate?
Have you seen any data where you did observe amoxicillin resistance in H Pylori that is accurate? Or until now no such verifiable sources have been reported?
Is there any reason why H Pylori can't get resistant to Amoxicillin as opposed to other antibiotics?
Have you seen any data where you did observe amoxicillin resistance in H Pylori that is accurate? Or until now no such verifiable sources have been reported?
Is there any reason why H Pylori can't get resistant to Amoxicillin as opposed to other antibiotics?
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Re: RESISTANCE TO AMOXICILLIN IN H PYLORI?
We have not seen a real amoxicillin resistant case ourselves.
in most of the resistant articles, they use a lower cut-off threshold. But since amoxicillin is so safe, and can be given in high dose, there is no need to use a lower cut-off threshold.
We are not sure why is amoxicillin so hard to be resistant to. Perhaps the gene involved is so important that it does not tolerate any mutation.
in most of the resistant articles, they use a lower cut-off threshold. But since amoxicillin is so safe, and can be given in high dose, there is no need to use a lower cut-off threshold.
We are not sure why is amoxicillin so hard to be resistant to. Perhaps the gene involved is so important that it does not tolerate any mutation.