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Should i be okay ?

Posted: Tue May 24, 2016 9:52 am
by hpsam
Hi all,
Need some help.
I tested HP positive via a stool test on 03/04/2016
Started triple therapy on 03/31/2016. Clarithomycim 500mg 2 x20 days, Metronidazole 500 mg 3x10 days and 40mg Omprazole once daily
Retest on 05/09/2016 via a stool test. Positive.
05/13/2013 put on quadruple therapy. Tetracycline 500mg 4 x 14 days, Metronidazole 250 mg 4 x 14 days,20mg Omprazole one a day and bismuth subsalicylate 262mg 2 tablets 4 times a day for 10 day. Had to take the antibiotics and the bismuth at least 2 hours apart to stop possible interaction.

I just stopped the Quad treatment after a full 10 days. I could not continue the treatment. The side effect were to much. I think the Dr put me on the second course to quickly after the first course.I tolerated the first course without any problems.

Do you think 10 days of the quad treatment will be enough.The dosage seem quite high and from what i have read the standard Quadruple therapy treatment time(pylera ?)is usually 7 to 10 days. Would the 4 extra days have made much difference?

Thanks for the support

Re: Should i be okay ?

Posted: Tue May 24, 2016 7:51 pm
by hpsam
Hi helico
expert. Please advise

Re: Should i be okay ?

Posted: Tue May 24, 2016 10:32 pm
by Helico_expert
we treat our patients on a 10 day course and manage to get a cure rate of over 90%.

14 days is known to be better than 10 days, but probably push another 3-5%.

So, I think you should be fine. Let's wait and see your follow up stool test.

Re: Should i be okay ?

Posted: Tue May 24, 2016 11:18 pm
by hpsam
Thank you.

How long should i stay on the 20mg daily omprezole after i am done with the antibiotic. My primary care Dr only gave 5 more days supply. The specialist said i should stay on for 30 days or the treatment will not work.

Re: Should i be okay ?

Posted: Wed May 25, 2016 9:08 am
by Helico_expert
most people stop PPI straight away after stopping antibiotics. Unless the doctor suspect ulcer, then patients are recommend to take additional 30 days PPI. that should give enough time for the ulcer to heal under a non acidic environment.

Nevertheless, after you finish the PPI, If you still experience acid reflux, you can switch to a weaker acid blocker like Ranitidine. It is safer and you can continue using Ranitidine until the day before the follow up test.

Re: Should i be okay ?

Posted: Thu May 26, 2016 12:02 am
by hpsam
I did not have an endoscopy done so i dont know if the Dr knows for sure if i have/had an actual ulcer. I was having pain in the middle of my chest mainly in the day bur rarely at night. I have been on the ppi on and off since January 2016. I have heard they are difficult to come of and can have a rebound reflux effect that can cause more damage.Can coming of the ppi now effective the H pylori treatment or should i try

Re: Should i be okay ?

Posted: Thu May 26, 2016 4:51 pm
by Helico_expert
Yea, some doctors think it is not necessary to check for ulcer. because with or without ulcer, just put you on PPI for a month. Easy management. One month PPI is not going to do you harm and if you do have ulcer, you'll recover after one month of PPI.

Re: Should i be okay ?

Posted: Thu Jun 02, 2016 10:19 pm
by hpsam
Hello Expert,

I stopped taking the ppi on 05-29-2016. Last night the pain in my chest returned again but alot worse then before.I noticed by poop is black this morning. I took the 20mg ppi last night and also 150gm of zantac. I am feeling alot better this morning. Do you think i should stay on the ppi for another 30 days. I am only taking 20mg once a day. Should i also take the zantac daily. Does it sound like i have an ulcer. Other then the ppi what else can i do.

Re: Should i be okay ?

Posted: Fri Jun 03, 2016 12:42 am
by Helico_expert
I think you need to speak to your doctor. See if you are able to book yourself an endoscopy examination. meanwhile, you can control your symptoms with PPI and ranitidine.

Re: Should i be okay ?

Posted: Fri Jun 03, 2016 12:57 am
by hpsam
Can i do an endoscopy while i am taking the ppi and zantac