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Stopped Quadruple Therapy after 12 days and it's getting even worse

The cure of Hp usually requires antibiotics. Other things have been tried and have a weaker effect.

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jiayubeauty
Posts: 2
Joined: Mon Sep 24, 2018 9:48 am

Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by jiayubeauty »

I just took the quadruple therapy for 12 days, although the doctor said I should take for 14 days but I cannot take it anymore.
The side effect is horrible, not only black tongue and black poop due to bismuth, but also belching, bloating, and heartburning after almost every meal!! I'm eating very little and have lost 5 pounds in a week.
and today is the 4th day after I've stopped the therapy, but the symptoms are still there OMG!! I think I'm having anxiety and depression now due to all happened in the past 3 weeks and it's driving me crazy.
Can anyone share your experience and give me any hope?

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by Helico_expert »

12 days is probably good enough. Prof Marshall usually only use 10 days treatment.

so which quadruple therapy did you use?

it's normal not to feel "cured" immediately. Some people takes months or years to get back to normal. Most importantly is to know that H. pylori is eradicated and your situation will not get worse.

So make sure you make another appointment a month later to get your HP checked and make sure it is truly eradiated.

museaddict
Posts: 34
Joined: Fri Jun 01, 2018 4:51 pm

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by museaddict »

did you do PYLERA ?
I think PYLERA treatment it's only for 10 days

jiayubeauty
Posts: 2
Joined: Mon Sep 24, 2018 9:48 am

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by jiayubeauty »

my therapy was Lansoprazole + Tetracycline +Metronidazole + Bismuth

museaddict
Posts: 34
Joined: Fri Jun 01, 2018 4:51 pm

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by museaddict »

I think it's the strongest therapy you taken it's Pylera formula H.pylori should not resist to that

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by Helico_expert »

It is hard for H. pylori to become resistant to Tetracycline. But easy to become resistant to metronidazole. However, there are evidence that metronidazole resistance can be overcome when taking tetracycline or higher dose.

Anyway, you will have to do another breath test a month later to confirm the eradication.

museaddict
Posts: 34
Joined: Fri Jun 01, 2018 4:51 pm

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by museaddict »

Helico_expert wrote:
Tue Sep 25, 2018 12:23 pm
It is hard for H. pylori to become resistant to Tetracycline. But easy to become resistant to metronidazole. However, there are evidence that metronidazole resistance can be overcome when taking tetracycline or higher dose.

Anyway, you will have to do another breath test a month later to confirm the eradication.
I read that you could take metronidazole again if the bacteria has already resisted to metronidazole but with another combination
is that true ?

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Stopped Quadruple Therapy after 12 days and it's getting even worse

Post by Helico_expert »

yes it is true that metronidazole resistance can be overcome when taking tetracycline or higher dose.

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