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Treatment related to h pylori

Posted: Thu Dec 27, 2018 1:37 am
by Jpp
Hello sir one day in morning time i took clarithromycin ppi but forgot to take the dose of Amixocillin . So i took that dose in the afternoon tym. Is that cause any problem sir?? Plz reply

Re: Treatment related to h pylori

Posted: Thu Dec 27, 2018 9:11 am
by Helico_expert
That's ok. I have also responded in the following link.

viewtopic.php?f=14&t=206141

Re: Treatment related to h pylori

Posted: Tue Feb 05, 2019 6:20 pm
by Jpp
Hello sir, In the past Before many times due to cold cough problems i took AZYTHROMYCIN nd cold tablets usually pharmacist give me these for cold cough. Will it cause resistance to AZYTHROMYCIN for h pylori ? Recently i had tripple therapy OAC. Reply sir

Re: Treatment related to h pylori

Posted: Wed Feb 06, 2019 2:12 pm
by Helico_expert
yes, previous exposure to Azithromycin can cause resistant in H. pylori. Resistant to Azithromycin also leads to Clarithromycin. So you cannot take any of these drug anymore in your next treatment.

Re: Treatment related to h pylori

Posted: Mon Feb 11, 2019 8:03 pm
by Jpp
Amoxicillin also cause resistance in h pylori ? because i have also taken Amoxicillin in the first line treatment ... Are there Amoxicillin resistant h pylori strains?
Please guide sir...

Re: Treatment related to h pylori

Posted: Mon Feb 11, 2019 10:35 pm
by Helico_expert
H. pylori cannot become resistant to Amoxicillin.

Although there are articles out there that claim about Amoxicillin resistant H. pylori strain, it is because they are using lower cut off value. Since we can take amoxicillin in high concentration, there is no need to use lower cut off value just to claim they are resistant.

Re: Treatment related to h pylori

Posted: Wed Feb 20, 2019 12:33 am
by Jpp
I am on ppi for years .. if i don't take ppi i have acidity nd sour stomach. How to wean off ppi? Please sir guide me. Any suggestions

Re: Treatment related to h pylori

Posted: Wed Feb 20, 2019 7:26 am
by Helico_expert
first of all, you need to make sure that you are free of H. pylori. the catch is that you need to stop PPI before the breath/stool test. So, you can try switch to ranitidine for a while and see if it helps.

ranitidine is a fast acting acid blocker, but short live in the body. PPI is a slow acting acid blocker and have longer live in the body. PPI normally shows a better inhibition in acid secretion. because ranitidine is short live, you need to time yourself very well, eg. 30 min before the acid comes (usually before meal time).

the advantage of ranitidine is that it will not affect the breath/stool test. you can continue ranitidine until the night before breath/stool test.

your stomach can only truly recover without H. pylori. hence it is important to find out.

Re: Treatment related to h pylori

Posted: Wed Feb 20, 2019 9:49 am
by Jpp
Has Ranitidine any acid rebound effect after withdrawal like ppi ?

Re: Treatment related to h pylori

Posted: Wed Feb 20, 2019 8:29 pm
by Helico_expert
less likely. you can stop ranitidine anytime, but PPI usually requires you to stop gradually.