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Suggestions for third line treatment .

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puttahm
Posts: 6
Joined: Mon Jul 23, 2018 2:31 am

Suggestions for third line treatment .

Post by puttahm »

Hello !!

At first i was diagnosed with Hpylori on 06/11/2017 .
doctor prescribed medicine kit of Clarithromycin-500 mg /amoxcillin -750 mg/esomeprazole -40mg (SOMPRAZ HP KIT) for 10 days .
it helped me in reducing my symptoms and feel better some symptoms were still persisting.

On next follow up doctor didn't prescribe eradication test and i continued to stay calm hoping for cure ,
so on 02/05/2018 i got UBT done and results came out positive (with Dl length difference of 5.3 MM) .
so then my doctor prescribed me the same kit(SOMPRAZ H P) for 10 days ,

And now today 01/08/2018 i took UBT and results came out Positive again (with dL length difference of 6.8mm).
so tomo i have appointment with my Dr , i am concerned if he suggests same treatment regime.
please give suggestions on my condition ?
is it that bacterial resistance on prescribed medicines above is not eradicating the infection completely ?
thank you:)

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Suggestions for third line treatment .

Post by Helico_expert »

your doctor shouldnt give you the same treatment. when the first treatment failed, the HP is obviously resistant to the treatment.

HP will never become resistance to Amoxicillin and bismuth. So you can use these two antibiotics repetitively.

Try to ask your doctor to give you PPI + Amox + Metrodidazole + bismuth (or tetracycline).

puttahm
Posts: 6
Joined: Mon Jul 23, 2018 2:31 am

Re: Suggestions for third line treatment .

Post by puttahm »

Many thanks for the response !!

Pls provide ur view on- Is it my bacterial condition has not eradicated completely starting from initial treatment to till date ? Or is it that it's regrowing again after the course of medicine ?

Thank u :)

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Suggestions for third line treatment .

Post by Helico_expert »

It is likely that your H. pylori wasnt killed in the first round. You may feel better as majority of them were killed. Then those resistant one, in small number, through time, grow up in mass and you start feeling the symptoms.

Then you were given the second treatment, but the same antibiotics as your previous treatment. The H. pylori strains already gain resistance to the antibiotics. Some of them may die, but majority of them will survive. You may feel better from the PPI suppressing the acid. But the root of the problem is still there.

So you will need to make sure H. pylori is completely eradicated in order to start feeling better. It's not easy for adult to catch H. pylori back. because I assume most adult would look after their own personal hygiene. eg. brushing teeth and washing hands.

puttahm
Posts: 6
Joined: Mon Jul 23, 2018 2:31 am

Re: Suggestions for third line treatment .

Post by puttahm »

Many many thanks for the reply ☺️
Thanks for providing this beautiful platform for the needy to get help !!

Meanwhile I will update here after consulting my Dr tonight 😊

Thank u 😊

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Suggestions for third line treatment .

Post by Helico_expert »

Good luck to your treatment and do keep us posted.

puttahm
Posts: 6
Joined: Mon Jul 23, 2018 2:31 am

Re: Suggestions for second line treatment .

Post by puttahm »

Hii!

With respect to above conversations , my doctor asked me to visit after one month ( he dint wanted to prescribe antibiotics after UBT +ve, bec I had took those medicines before a month so as it will affect intestines so next time I visit he wanted to do re endoscopy to re confirm infection and start second line treatment ) after one month today he dint do endoscopy !!

My Present symptoms include :
1: Fat Mal Absorption ( unable to gain weight which I lost during infection )
2: stomach acid issues , indigestion .
3: Issues related to mind( brain fog and other symptoms )
So doctor says hpylori doesn't affect fat malabsorption so he prescribed me some blood tests to check for cause behind fat malabsorption ( blood tests-Hba1c, TSH,ESR,CBC,creatine serum , albumin serum )
And if these tests come out negative he has prescribed these medicines (Simly Mct oil, lamino GI,PankreoFlat ) which has to be taken for one month , if no improvements he wants to do CT abdomen , If that comes out normal he will then do endoscopy and start second line treatment for hpylori !! Hell !!
I've become Mad !!
It's been one year treating for my hpylori and it's still going on ..


(I'm very sure all the blood tests will come -ve( last time also it came out -ve), and if he does CT scan also I believe it will be normal)
All my symptoms ,problems started with hpylori and all existing problems also I believe bec of hpylori .My doctor is very casual about hpylori infection , he says having it +ve is not big deal.

I'm really confused ..
Please suggest me something ..
Shall I ask for second line treatmet straightly by Dr, or shall I follow his procedure ..
Does Hpylori causes fat malabsorption ?

Thank u

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Suggestions for third line treatment .

Post by Helico_expert »

I agree with your doctor that HP doenst cause fat mal-absorption. Also, to avoid false negative result, you are required to stop all drugs for a month before breath test or endoscopy.

puttahm
Posts: 6
Joined: Mon Jul 23, 2018 2:31 am

Re: Suggestions for third line treatment .

Post by puttahm »

Thanks for the reply!!

My hpylori is not yet cured to negative , it's still positive !
As I said after last UBT result (which came out positive )Dr did not prescribe antibiotics after test for eradication.. So still it's present in my stomach !! Dr says I need not worry about the infection being positive and didn't prescribe medicines for infection saying we will treat it later .
Having it in stomach is the reason for body not able to gain weight ?
And yeah I was free from medicines fr more than month before UBT.

A small update , as I said earlier my blood reports would be normal , now I got my reports and it's absolutely normal .

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Suggestions for third line treatment .

Post by Helico_expert »

If you are H. pylori positive, then you should get treatment. Seek 2nd opinion if required. Remember not to use antibiotics that you had previously tried. except for Amoxicillin and Bimuth. H. pylori cannot become resistant to Amox and Bismuth.

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