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Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
The 5th Chinese Helicobacter treatment consensus
How long should I wait before doing follow up breath/stool test?

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欧洲幽门螺杆菌治疗共识 5
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Recently diagnosed

The cure of Hp usually requires antibiotics. Other things have been tried and have a weaker effect.

Moderators: barjammar, Toni, luci2010, Ondek-Expert, kkimura

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Scatterbrain
Posts: 2
Joined: Sat Mar 02, 2019 6:11 pm

Recently diagnosed

Post by Scatterbrain »

I was recently diagnosed through a GI Map with h-pylori (2.2e3, normal = <1.0e3) virulence factor babA, campylobacter (5.56e3, normal = <1.00e3), staphylococcus (1.35e4, normal = <1.00e4) and steatocrit (40, normal = < 15%).

I don't have any stomach pain, acid reflux, indigestion etc. My main symptoms have been bloatedness after eating and drinking, weight loss, even though appetite good and undigested food in stools.

Are these symptoms likely to all be from h-pylori or will some of them be from the other gut infections? Also, will one course of antibiotics, however many necessary at once, clear all these infections or will I need separate courses for each?

Thanks in advance.

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Recently diagnosed

Post by Helico_expert »

H. pylori is associated with many stomach problem. including bloating, pain, lost of appetite, etc..

However, GI Map is not the recommended tool for H. pylori diagnosis. You should go to your doctor and ask for breath or stool test to double confirm, before taking antibiotics.

In terms of treatment success rate, it depends on how frequent you are expose to antibiotics. In country like China where Antibiotics are abused, trace of antibiotics can be found in drinking water and food. So the antibiotic resistance is high and treatment success rate is low. In Australia, the one course of standard triple therapy has a cure rate of above 80%. However, in many European countries, standard triple therapy only has cure rate below 60% and has already been abandoned.

The "success" of treatment here is defined as the removal of H. pylori. Removal of H. pylori may or may not eradicate your current symptoms. For those with severe symptoms usually would experience better improvement in overall quality of life. For people with little to no symptoms, they normally do not feel the improvement and for a small group of people, due to the antibiotics killing off the good bacteria in the guts, may develop IBS.

Nevertheless, we still recommend the removal of H. pylori because it is associated with stomach ulcer and cancer. For young people where they are young and healthy, they are most likely asymptomatic. However, as they get older, their immune system and repair mechanism get poorer, the wound cause by H. pylori may become irreversible. Then it may be too late for a cure.

Scatterbrain
Posts: 2
Joined: Sat Mar 02, 2019 6:11 pm

Re: Recently diagnosed

Post by Scatterbrain »

Thank you for your comprehensive reply.

I thought that the GI Map test was accurate because it is a stool test? Am I wrong and, if so, is it possible that this test could cause false positive results then? This is used regularly in UK and US by functional medicine practitioners.

Helico_expert
Site Admin
Posts: 4600
Joined: Wed Mar 02, 2011 7:20 am

Re: Recently diagnosed

Post by Helico_expert »

GI Map is a very new thing. I believe it's using DNA detection method. At the moment, DNA testing has a lot of false positive. Nevertheless, I have not verify it myself. So the actual sensitivity and specificity towards H. pylori is not known.

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