Therapies

Proven Therapies

GENERIC NAME	DOSING	DURATION	CURE RATE (%)
bismuth subsalicylate	Two tablets (525 mg) QID	7 days	85-95
or			*( see note below)**
Colloidal bismuth subcitrate	One tablet (120 mg) QID	14 days
metronidazole	250 mg QID	7 days
tetracycline	500 mg QID	7 days
omeprazole	20 mg BID	7 days
or
lansoprazole	30 mg BID	7 days

GENERIC NAME	DOSING	DURATION	CURE RATE (%)
Colloidal bismuth subcitrate	120mg QID	14 days	72%
Furazolidone	100mg BID ***	14 days
Amoxycillin	1000mg BID	14 days
Omeprazole	20mg BID	14 days
	Double Furazolidone dose
Colloidal bismuth subcitrate	120mg QID	14 days	92%
Furazolidone	200mg BID***	14 days
Amoxycillin	1000mg BID	14 days
Omeprazole	20mg BID	14 days

GENERIC NAME	DOSING	DURATION	CURE RATE (%)
Amoxycillin	1000mg BID	14 days	90-92%
Omeprazole	40mg TDS (6 times normal dosage)	14 days
Ciprofloxacin	500mg BID	14 days
Rifabutin	150mg BID	14 days

	Cammarota et.al. (2000)
Rabeprazole (R)	20mg QD	7 days
Levofloxacin (L)	500mg QD	7 days	RLA Cure rate=92%
Amoxycillin (A)	1000mg BID)	7 days

Tinidazole (T)	500mg (BID)	7 days	RLT Cure rate =90%

	Nagahara et al. (2000)
Rabeprazole (R)	10mg BID	5 days
Amoxicillin (A)	750mg BID	5 days
Clarithromycin (C)	200mg BID	5 days	RAC Cure rate 86.7%(PP) 80% (ITT)
Metronidazole (M)	250mg BID	5 days	RACM Cure rate 98.1% (PP) 94.5% (ITT)

	Luth et al (2001)
Rabeprazole	20mg BID	4 days
Clarithromycin	500mg BID	4 days	Cure Rate =90%
Amoxycillin	1000mg BID	4 days

	Wong et al. 2003
Rabeprazole	20mg BID	7 days	Cure rate 91% (PP)
Rifabutin	300mg QD	7 days	Cure rate 91% (ITT)
Levofloxacin	500mg QD	7 days

	Wong et al (2003)
Rabeprazole	20mg BID	7 days
Colloidal Bismuth Subcitrate	120mg QID	7 days	Cure rate 92% (PP)
Metronidazole	400mg TID	7 days	Curea rate 91%(ITT)
Tetracycline	500mg QID	7 days

*Note: In some countries they have found that 7 days therapy with this regimen is equally effective.